Enlarged Spleen (Splenomegaly) – Symptoms, Causes and Treatment Options

 The spleen is an organ located in the upper left side of the abdomen, under the ribcage. It is part of the immune system and plays various roles in the body, including filtering and storing blood, removing damaged blood cells, producing certain immune cells, and storing platelets. The spleen also helps regulate blood flow and acts as a reservoir for blood in emergencies, such as bleeding or shock. The spleen also helps to fight infections in the body and keep immunity protected. Infectious and harmful blood passing through the spleen may also swell the body’s organs.


An enlarged spleen, or splenomegaly, is a medical condition in which the spleen becomes larger than its normal size. This can be caused by various underlying health issues, such as infections, certain medical conditions, blood disorders, liver disease, inflammatory conditions, and sometimes cancer. The condition also indicates a weak immune system and can be identified by symptoms such as abdominal pain. One may also experience internal bleeding. The organ may also rupture if the condition is not cured on time. The state can be identified by extreme pain on the left side of the abdomen or feeling full most of the day.




Symptoms of Enlarged Spleen

Mentioned below are some of the enlarged spleen symptoms helping in identification at the right time and beginning the treatment:


Abdominal Pain– Pain in the upper left side of the abdomen is one of the identifiable symptoms of a damaged spleen. The enlarged organ presses against the stomach, causing pain, and if not treated at the right time, the pain may turn extreme. In case of such symptoms, a doctor should check the condition to know the root cause and begin the proper form of medication and treatment. If the situation worsens, the individual may also feel pain in the left shoulder.

Feeling Full– An enlarged spleen due to different medical conditions may make the affected appetite feel full without consuming food. The affected patient cannot finish the required nutrients and may face other health conditions.

Easy Bruising and Bleeding- An enlarged spleen can trap and remove platelets essential for blood clotting, leading to an increased risk of bruising and bleeding.

Frequent Infections- The spleen is part of the immune system; its dysfunction can increase vulnerability to infections.

Anaemia– One of the most extensive symptoms of the disease is anaemia. It happens due to destroyed red blood cells. The affected individual feels weak, tired and may also experience fatigue. The red blood cells may ruin due to improper functioning of the Spleen and its enlargement. Easy internal bleeding is also one of the symptoms of the disease.

Painful Breathing- If the enlarged spleen presses against the diaphragm, it may cause discomfort or pain during deep breaths.

Enlarged Liver- An enlarged spleen is sometimes accompanied by an enlarged liver (hepatosplenomegaly).




Contents hide

1 Overview

2 Symptoms of Enlarged Spleen

3 Causes of Splenomegaly

4 Treatment Options for Enlarged Spleen

5 When to Consult a Doctor

6 Conclusion

7 FAQs

Overview

The spleen is an organ located in the upper left side of the abdomen, under the ribcage. It is part of the immune system and plays various roles in the body, including filtering and storing blood, removing damaged blood cells, producing certain immune cells, and storing platelets. The spleen also helps regulate blood flow and acts as a reservoir for blood in emergencies, such as bleeding or shock. The spleen also helps to fight infections in the body and keep immunity protected. Infectious and harmful blood passing through the spleen may also swell the body’s organs.


An enlarged spleen, or splenomegaly, is a medical condition in which the spleen becomes larger than its normal size. This can be caused by various underlying health issues, such as infections, certain medical conditions, blood disorders, liver disease, inflammatory conditions, and sometimes cancer. The condition also indicates a weak immune system and can be identified by symptoms such as abdominal pain. One may also experience internal bleeding. The organ may also rupture if the condition is not cured on time. The state can be identified by extreme pain on the left side of the abdomen or feeling full most of the day.


Symptoms of Enlarged Spleen

Mentioned below are some of the enlarged spleen symptoms helping in identification at the right time and beginning the treatment:


Abdominal Pain– Pain in the upper left side of the abdomen is one of the identifiable symptoms of a damaged spleen. The enlarged organ presses against the stomach, causing pain, and if not treated at the right time, the pain may turn extreme. In case of such symptoms, a doctor should check the condition to know the root cause and begin the proper form of medication and treatment. If the situation worsens, the individual may also feel pain in the left shoulder.

Feeling Full– An enlarged spleen due to different medical conditions may make the affected appetite feel full without consuming food. The affected patient cannot finish the required nutrients and may face other health conditions.

Easy Bruising and Bleeding- An enlarged spleen can trap and remove platelets essential for blood clotting, leading to an increased risk of bruising and bleeding.

Frequent Infections- The spleen is part of the immune system; its dysfunction can increase vulnerability to infections.

Anaemia– One of the most extensive symptoms of the disease is anaemia. It happens due to destroyed red blood cells. The affected individual feels weak, tired and may also experience fatigue. The red blood cells may ruin due to improper functioning of the Spleen and its enlargement. Easy internal bleeding is also one of the symptoms of the disease.

Painful Breathing- If the enlarged spleen presses against the diaphragm, it may cause discomfort or pain during deep breaths.

Enlarged Liver- An enlarged spleen is sometimes accompanied by an enlarged liver (hepatosplenomegaly).

Causes of Splenomegaly

Infection- One of the primary reasons for the enlarged organ is infection caused due to bacteria and viruses. Different conditions, such as HIV, mononucleosis, tuberculosis, endocarditis, and malaria, can also damage the Spleen and enlarge it.

Pressurised Blood Vessels– Pressurised blood vessels of the Spleen can also enlarge the purifying organ. The blood vessels can enlarge due to different types of liver diseases, such as chronic hepatitis, cirrhosis, and other similar disorders. Pooling of blood in the blood vessels can also enlarge the Spleen.

Cancer– The leading cause of cancer is the multiplication of cancerous cells damaging a specific body organ. Different types of blood cancers, such as leukaemia or lymphomas, lead to blood passing through the Spleen, spreading cancer in the organ.

Blood Disorders– Different blood disorders, such as hemolytic anaemia or neutropenia, are also significant causes of enlarged spleen. Blood disorders lead to multiple health disorders, such as blood clotting, pressurising of blood vessels, and various other illnesses. The disorder also leads to low production of white blood cells, lowering the affected patient’s immunity. The disorder can be cancerous or noncancerous. The condition can also be identified by heavy bleeding in case of an injury.

Metabolic Disorders– Building up various substances in the blood leads to blockage in its flow, and accumulation of debris in different body organs can also lead to an enlarged spleen. These disorders can be inherited or occur due to the weak immunity of the affected individual. Various inherited metabolic disorders, such as lysosomal storage disorder, glycogen storage diseases, peroxisomal disorders, and other similar disorders, can infiltrate the blood.

Thrombosis– It is also one of the major causes of spleen disorder. It is a medical condition in which the blood vessels block due to different health conditions leading to a blood clot. It pressurises the blood vessels enlarging the organ, leading to several other health issues. Damage inside the blood vessels or slowed blood flow is the primary reason for the complication damaging the functioning of the Spleen.

Autoimmune Diseases– Different autoimmune diseases such as rheumatoid arthritis, systemic lupus, Gaucher disease, and other similar diseases can also enlarge the Spleen. Such health conditions lower the immunity of an individual to fight different types of bacterial or viral infections.

Liver Diseases- Liver conditions such as cirrhosis, hepatitis, and portal hypertension can cause blood to back up into the spleen, leading to enlargement.

Congestion and Obstruction- Blockages in the blood vessels of the spleen, often due to blood clot formation, can lead to increased pressure and splenomegaly.

Inflammatory Conditions- Autoimmune disorders, such as lupus, rheumatoid arthritis, and sarcoidosis, can trigger inflammation and result in splenomegaly.



Congestion and Obstruction- Blockages in the blood vessels of the spleen, often due to blood clot formation, can lead to increased pressure and splenomegaly.

Inflammatory Conditions- Autoimmune disorders, such as lupus, rheumatoid arthritis, and sarcoidosis, can trigger inflammation and result in splenomegaly.

Treatment Options for Enlarged Spleen

Mentioned below are some of the treatment options or methods that can help treat the disease:


Medications- In some cases, medicines may be prescribed to manage specific conditions contributing to splenomegaly. For example, antibiotics for infections, immunosuppressive drugs for autoimmune disorders, or chemotherapy for certain cancers.

Lifestyle Modifications- Depending on the underlying cause, lifestyle changes such as maintaining a healthy diet, managing weight, and avoiding activities that could lead to injury may be recommended.

Surgery- In severe cases or when other treatments are ineffective, surgical removal of the spleen may be considered. This is known as a splenectomy. However, this procedure increases the risk of infections and requires lifelong precautions (such as vaccinations) due to the spleen’s role in the immune system.

Avoiding Contact Sports- If the spleen is enlarged, it becomes more vulnerable to injury, so participating in contact sports might be discouraged.

Vaccinations- People with an enlarged spleen are at increased risk of certain infections. Vaccinations against bacterial infections such as pneumococcus, Haemophilus influenzae type b (Hib), and meningococcus may be recommended.



Conclusion

Enlarged Spleen is a medical condition in which the spleen enlarges due to different medical issues. It can be identified by symptoms such as abdominal and shoulder pain, feeling full most of the time, and easy bleeding. It heals with the help of medications or surgery.


FAQs

Q. What is an Enlarged Spleen?

A. It is a medical scenario in which a spleen enlarges, leading to health symptoms such as pain in the left side of the abdomen and left shoulder and high internal bleeding.


Q. What are the symptoms of an Enlarged Spleen?

A. The medical disease has health symptoms such as a full appetite without eating much food, pain in the upper left side of the abdomen, pain in the left shoulder, anaemia, and other similar issues.


Q. What are the causes of Splenomegaly?

A. Splenomegaly, or an enlarged spleen, can result from various causes, including infections (like mononucleosis), liver diseases (such as cirrhosis), blood disorders (like leukaemia), and inflammatory conditions. Trauma, certain cancers, and genetic conditions can also contribute. Diagnosis involves medical evaluation to identify the underlying cause for appropriate treatment.


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